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High-Resolution Computed Tomography of the Lung in Children with Cystic Fibrosis

Technical Factors

¹ Department of Radiology, Columbus Children's Hospital, Ohio State University, Columbus, Ohio

Correspondence and requests for reprints should be addressed to Frederick R. Long, M.D., Columbus Children's Hospital, A-1010, Department of Radiology, 700 Children's Drive, Columbus, OH 43205–2696. E-mail: flong{at}chi.osu.edu

ABSTRACT

A standard technique that controls for respiratory motion and lung volumes during imaging is necessary if high-resolution computed tomography is to be used as an outcome measure in children with cystic fibrosis. End-inspiratory and expiratory imaging allows for the detection and differentiation of early lung disease. In children ages 0–5 years, a noninvasive controlled ventilation technique is ideal, and can be used in combination with raised-volume infant pulmonary function tests. In older children, a spirometric-assisted or spirometric-triggered technique should be used. With optimal technique, radiation dose settings (kVp and mA) can be lowered to achieve a diagnostic screening high-resolution computed tomography of the lungs at a dose equivalent to that of the chest radiograph.

Key Words: computed tomography, infants and children • computed tomography, radiation dose • lung, high-resolution computed tomography • positive-pressure ventilation, methods

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Computed Tomography Scanning Techniques for the Evaluation of Cystic Fibrosis Lung Disease

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Proceedings of the American Thoracic Society 2007 4: 310-315. [Abstract] [Full Text]  

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