Proceedings of the American Thoracic Society Email Content Delivery
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

The Proceedings of the American Thoracic Society 4:554-564 (2007)
© 2007 The American Thoracic Society
doi: 10.1513/pats.200701-003FM
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Anzueto, A.
Right arrow Articles by Martinez, F. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Anzueto, A.
Right arrow Articles by Martinez, F. J.

Exacerbations of Chronic Obstructive Pulmonary Disease

Antonio Anzueto1, Sanjay Sethi2 and Fernando J. Martinez3

1 South Texas Veterans Health Care System, Audie L. Murphy Division, and the University of Texas Health Science Center at San Antonio, San Antonio, Texas; 2 State University of New York and Western New York Veterans Health Care System, Buffalo, New York; and 3 Division of Pulmonary and Critical Care Medicine at the University of Michigan, Ann Arbor, Michigan

Correspondence and requests for reprints should be addressed to Antonio Anzueto, M.D., Pulmonary/Critical Care (111E), University of Texas Health Science Center, 7400 Merton Minter Boulevard, San Antonio, TX 78229. E-mail: anzueto{at}uthscsa.edu

ABSTRACT

The diagnosis and treatment of acute exacerbations (AEs) of chronic obstructive pulmonary disease (COPD) is controversial. In this section, we review (1) the epidemiology of this condition; (2) the etiology—many patients with AECOPD are thought to have a combination of viral and bacterial infections, which contribute to their exacerbation. Bacterial organisms are isolated more commonly after viral infections in patients with COPD. The role that bacterial infections play in AECOPD remains a very controversial topic; (3) the use of diagnostic procedures; (4) efficacy of antibiotics; (5) clinical parameters to stratify patients' severity; (6) different groups of antibiotics that can be used; and (7) other therapies, including bronchodilators. We summarize the current literature, with special emphasis on the assessment of the long-term impact of this condition.

Key Words: acute exacerbations • antibiotics • chronic obstructive pulmonary disease • Haemophilus influenzae • Streptococcus pneumoniae




This article has been cited by other articles:


Home page
 Eur Respir JHome page
W-T. Liu, C-H. Wang, H-C. Lin, S-M. Lin, K-Y. Lee, Y-L. Lo, S-H. Hung, Y-M. Chang, K.F. Chung, and H-P. Kuo
Efficacy of a cell phone-based exercise programme for COPD
Eur. Respir. J., September 1, 2008; 32(3): 651 - 659.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
A. Punturieri, T. L. Croxton, G. G. Weinmann, and J. P. Kiley
Chronic Obstructive Pulmonary Disease: A View from the NHLBI
Am. J. Respir. Crit. Care Med., September 1, 2008; 178(5): 441 - 443.
[Full Text] [PDF]

Home page
 Proc Am Thorac SocHome page
A. Singh
On Treating and Preventing Acute Exacerbations in COPD
Proceedings of the ATS, February 15, 2008; 5(2): 283 - 283.
[Full Text] [PDF]

Home page
 Proc Am Thorac SocHome page
S. Sethi, A. Anzueto, and F. J. Martinez
On Treating and Preventing Acute Exacerbations in COPD
Proceedings of the ATS, February 15, 2008; 5(2): 283 - 283.
[Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2007 by the American Thoracic Society.