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The Proceedings of the American Thoracic Society 5:447-453 (2008)
© 2008 The American Thoracic Society
doi: 10.1513/pats.200707-107ET
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Lung Transplantation and Lung Volume Reduction Surgery versus Transplantation in Chronic Obstructive Pulmonary Disease

Namrata Patel1, Malcolm DeCamp2 and Gerard J. Criner1

1 Temple University School of Medicine, Philadelphia, Pennsylvania; and 2 Beth Israel Deaconess Medical Center, Boston, Massachusetts

Correspondence and requests for reprints should be addressed to Namrata Patel, M.D., Temple University School of Medicine, Temple Lung Center, Temple University Hospital, 3401 North Broad Street, Suite 785, Philadelphia, PA 19140. E-mail: pateln{at}tuhs.temple.edu

ABSTRACT

Lung transplantation and lung volume reduction surgery are surgical options for patients with advanced chronic obstructive pulmonary disease that is refractory to medical treatment. In this review, we discuss the differential indications for each procedure, as well as compare their risks and benefits. We also present an algorithm for selecting the most appropriate procedure for individual patients. Finally, we discuss the feasibility and role of lung transplantation after lung volume reduction surgery in the management of selected patients with chronic obstructive pulmonary disease.

Key Words: lung volume reduction surgery • lung transplantation • emphysema • advanced lung disease






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