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Comorbidities in Chronic Obstructive Pulmonary Disease

¹ Division of Pulmonary and Critical Care Division, Temple University School of Medicine, Philadelphia, Pennsylvania; ² Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York; ³ Department of Pulmonary, Allergy, and Critical Care Medicine, Cleveland Clinic Foundation, Cleveland, Ohio; and ⁴ Division of Pulmonary Sciences and Critical Care Medicine, National Jewish Medical and Research Center, University of Colorado School of Medicine, Denver, Colorado

Correspondence and requests for reprints should be addressed to Wissam Chatila, M.D., Division of Pulmonary and Critical Care Division, Temple University School of Medicine, 3401 N Broad Street, Philadelphia PA, 19140. E-mail: chatilw{at}tuhs.temple.edu

ABSTRACT

Comorbidities such as cardiac disease, diabetes mellitus, hypertension, osteoporosis, and psychological disorders are commonly reported in patients with chronic obstructive pulmonary disease (COPD) but with great variability in reported prevalence. Tobacco smoking is a risk factor for many of these comorbidities as well as for COPD, making it difficult to draw conclusions about the relationship between COPD and these comorbidities. However, recent large epidemiologic studies have confirmed the independent detrimental effects of these comorbidities on patients with COPD. On the other hand, many of these comorbidities are now considered to be part of the commonly prevalent nonpulmonary sequelae of COPD that are relevant not only to the understanding of the real burden of COPD but also to the development of effective management strategies.

Key Words: chronic bronchitis • obstructive lung disease • epidemiology

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				F. Luppi, F. Franco, B. Beghe, and L. M. Fabbri Treatment of Chronic Obstructive Pulmonary Disease and Its Comorbidities Proceedings of the ATS, December 1, 2008; 5(8): 848 - 856. [Abstract] [Full Text] [PDF]