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Medical Complications of Lung Transplantation

¹ Department of Medicine, University of Colorado at Denver, and Health Sciences Center, Denver, Colorado

Correspondence and requests for reprints should be addressed to Dennis M. Lyu, M.D., 1635 N. Ursula St. F749, Aurora, CO 80045. E-mail: dennis.lyu{at}uchsc.edu

ABSTRACT

As short- and long-term survival rates for lung transplantation continue to improve, and as more lung transplantations are occurring with each year, a multitude of medical complications are encountered by the clinician. This article reviews the long-term non-pulmonary noninfectious medical complications that arise beyond the postoperative period in patients who have undergone lung transplantation. This article reviews the development of renal failure, diabetes, cardiovascular complications of hypertension and atherosclerosis, osteoporosis and avascular necrosis, hematologic complications, thromboembolic disease, gastrointestinial complications, neurologic complications, and malignancy, including post-transplant lymphoproliferative disorder.

Key Words: medical complications • lung transplantation