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The Proceedings of the American Thoracic Society 6:218-223 (2009)
© 2009 The American Thoracic Society
doi: 10.1513/pats.200808-099LC
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Emerging Therapeutic Targets in Non–Small Cell Lung Cancer

Grace K. Dy1 and Alex A. Adjei1

1 Department of Medicine, Roswell Park Cancer Institute, Buffalo, New York

Correspondence and requests for reprints should be addressed to Alex A. Adjei, M.D., Ph.D., Katherine Anne Gioia Chair in Cancer Medicine, Roswell Park Cancer Institute, Elm & Carlton Streets, Buffalo, NY 14263. E-mail: alex.adjei{at}roswellpark.org

ABSTRACT

Over the last decade, systemic cancer therapies have evolved to exploit the growing knowledge of molecular aberrations involved in the development and progression of lung cancer. This review highlights the biological targets relevant in the treatment of non–small cell lung cancer.

Key Words: non–small cell lung cancer • vaccine • epidermal growth factor receptor • angiogenesis






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