Posters:

Riuping Song, Paul R. Reynolds, Carol Feghali-Bostwick, James C. Hogg, and Augustine M. K. Choi

Identification of New Molecular Pathways Involved in the Pathogenesis of Chronic Obstructive Pulmonary Disease by Proteomics Approaches
Proc Am Thorac Soc 2006 3 [Full Text] [PDF]  

Lukas Didon, Ingemar Qvarfordt, Olof Andersson, Magnus Nord, and Gerdt C. Riise

Decreased CCAAT/Enhancer Binding Protein (C/EBP)Transcription Factor Activity in Chronic Bronchitis and Chronic Obstructive Pulmonary Disease
Proc Am Thorac Soc 2006 3: 543. [Full Text] [PDF]  

Shyam Biswal, Tirumalai Rangasamy, and Rubin M. Tuder

Modifier Role of Nrf2 in Cigarette Smoke–induced Emphysema
Proc Am Thorac Soc 2006 3: 543. [Full Text] [PDF]  

Shuo Zheng, Daniel J. Kenan, Bernard M. Fischer, and Judith A. Voynow

Neutrophil Elastase Increases MUC5AC Mucin mRNA Expression via Post-Transcriptional Regulation
Proc Am Thorac Soc 2006 3: 543-544. [Full Text] [PDF]  

Masaharu Nishimura, Hironi Makita, Yasuyuki Nasuhara, Nobuyuki Hizawa, Tomoko Betsuyaku, and Hokkaido COPD Cohort Study Group

Phenotype Characterization Based upon High-Resolution Computed Tomography Findings and Reversibility of Airflow Limitation in Chronic Obstructive Pulmonary Disease
Proc Am Thorac Soc 2006 3: 544. [Full Text] [PDF]  

Ji-Hyun Lee, Eun-Kyung Kim, Doyeon Oh, Yeontae Chung, and Sang-Do Lee

Decreased Number of Circulating Endothelial Progenitor Cells in Patients with Emphysema
Proc Am Thorac Soc 2006 3: 545. [Full Text] [PDF]  

Dennis E. Doherty, Gretchen Lawrence, Louise M. Nett, and Thomas L. Petty

The National Lung Health Education Program (NLHEP)
Proc Am Thorac Soc 2006 3: 545. [Full Text] [PDF]  

Michiko Ito, Masayuki Hanaoka, Shintaro Kanda, Kazuhisa Urushihata, Tomonobu Koizumi, Keisaku Fujimoto, and Keishi Kubo

Pulmonary Hemodynamics in Patients with Chronic Obstructive Pulmonary Disease during Exercise and Exacerbation
Proc Am Thorac Soc 2006 3: 546. [Full Text] [PDF]  

James F. Donohue

Phosphodiesterase 4 Inhibitors in Chronic Obstructive Pulmonary Disease
Proc Am Thorac Soc 2006 3: 546. [Full Text] [PDF]  

Marc A. Voelkel, Jane Parr, Carlyne M. Cool, Murry W. Wynes, and David W. H. Riches

Interstitial and Peribronchial Macrophages in Chronic Obstructive Pulmonary Disease Display an Alternatively Activated Phenotype
Proc Am Thorac Soc 2006 3: 546-547. [Full Text] [PDF]  

Tetsu Kobayashi, Xiangde Liu, Tadashi Kohyama, Qiuhong Fang, Fu-Qiang Wen, Shinji Abe, Jeffrey Atkinson, James Shipley, Robert Senior, and Stephen I. Rennard

Matrix Metalloproteinase-9 Affects Three-Dimensional Collagen Gel Contraction
Proc Am Thorac Soc 2006 3: 547. [Full Text] [PDF]  

Shinsaku Togo, Xiangde Liu, Tetsu Kobayashi, Ronald F. Ertl, Hisatoshi Sugiura, Lei J. Shen, and Stephen I. Rennard

The PDE4 Inhibitors Roflumilast and Rolipram Modulate Fibroblast Collagen Gel Contraction and Chemotaxis Mediated by Autocrine PGE2 Synthesis Induced by Transforming Growth Factor-ß1
Proc Am Thorac Soc 2006 3: 547-548. [Full Text] [PDF]  

Trivikram Gaddapara, Mark O. Aksoy, Syed Shahabuddin, Rong Ji, Yi Yang, and Steven G. Kelsen

Acute Effects of Cigarette Smoke Extract on CXC Chemokines and Matrix Metalloproteinases Released by Airway Epithelial Cells
Proc Am Thorac Soc 2006 3: 548. [Full Text] [PDF]  

Yunchao Su, Jianliang Zhang, Jawaharlal M. Patel, Veena Antony, and Edward R. Block

Concentration-dependent Effects of Nitric Oxide on Angiogenesis of Lung Microvascular Endothelial Cells: Role of Calpain Nitrosylation
Proc Am Thorac Soc 2006 3: 548-549. [Full Text] [PDF]  

Irina Petrache, Iwona Fijalkowska, Lijie Zhen, Terry R. Medler, Jarrett Skirball, Terence Flotte, and Rubin M. Tuder

An Antiapoptotic Role for ₁-Antitrypsin in the Prevention of Emphysema
Proc Am Thorac Soc 2006 3: 549. [Full Text] [PDF]  

Sorachai Srisuma, Soumyaroop Bhattacharya, Temana Andalcio, Dawn M. Simon, Meltem C. Arikan, Barry Starcher, and Thomas J. Mariani

Fibroblast Growth Factor Receptor Signaling Regulates Extracellular Matrix Gene Expression during Alveogenesis
Proc Am Thorac Soc 2006 3: 549-550. [Full Text] [PDF]  

Bing Ma, Robert J. Homer, Chun G. Lee, Qingsheng Chen, Svetlana Chapoval, Anthony Coyle, Jose Lora, Dominic Picarella, and Jack A. Elias

Role of CC Chemokine Receptor 5 in Interferon-– and Cigarette Smoke–induced Emphysema
Proc Am Thorac Soc 2006 3: 550. [Full Text] [PDF]  

Xiangde Liu

RNAi against STAT3 Results in Cell Death in Human Bronchial Epithelial Cells Exposed to Cigarette Smoke Extract
Proc Am Thorac Soc 2006 3: 550-551. [Full Text] [PDF]  

Sanjay A. Patel, Augustine M. K. Choi, Yingze Zhang, Naftali Kaminski, Anna E. Lokshin, Joel L. Weissfeld, and Frank C. Sciurba

Systemic Biomarker Pattern in Different Chronic Obstructive Pulmonary Disease Phenotypes Independent of Smoking Status
Proc Am Thorac Soc 2006 3: 551. [Full Text] [PDF]  

Toshinori Yoshida, Tirumalai Rangasamy, Shyam Biswal, Irina Petrache, Igor Mett, Elena Feinstein, and Rubin M. Tuder

Role of RTP801, a Suppressor of the mTOR Pathway, in Cigarette Smoke–induced Pulmonary Injury in Mice
Proc Am Thorac Soc 2006 3: 551-552. [Full Text] [PDF]  

R. William Vandivier, Rubin M. Tuder, Konosuke Morimoto, Norbert F. Voelkel, and Peter M. Henson

Vascular Endothelial Growth Factor Regulates Clearance of Apoptotic Cells: Implications for Emphysema
Proc Am Thorac Soc 2006 3: 552. [Full Text] [PDF]  

Introduction:

Norbert F. Voelkel

Introduction
Proc Am Thorac Soc 2006 3: 459-460. [Full Text] [PDF]  

Section 1.:

Bartolome R. Celli

Roger S. Mitchell Lecture. Chronic Obstructive Pulmonary Disease Phenotypes and Their Clinical Relevance
Proc Am Thorac Soc 2006 3: 461-465. [Abstract] [Full Text] [PDF]  

Victor Pinto-Plata, John Toso, Kwan Lee, John Bilello, Hana Mullerova, Mary De Souza, Rupert Vessey, and Bartolome Celli

Use of Proteomic Patterns of Serum Biomarkers in Patients with Chronic Obstructive Pulmonary Disease: Correlation with Clinical Parameters
Proc Am Thorac Soc 2006 3: 465-466. [Full Text] [PDF]  

Wen Ning, Janet Lee, Naftali Kaminski, Carol A. Feghali-Bostwick, Simon C. Watkins, Joseph M. Pilewski, David G. Peters, James C. Hogg, and Augustine M. K. Choi

Comprehensive Analysis of Gene Expression on GOLD-2 Versus GOLD-0 Smokers Reveals Novel Genes Important in the Pathogenesis of COPD
Proc Am Thorac Soc 2006 3: 466. [Full Text] [PDF]  

Section 2.:

Ary L. Goldberger

Giles F. Filley Lecture. Complex Systems
Proc Am Thorac Soc 2006 3: 467-471. [Abstract] [Full Text] [PDF]  

Tomoko Betsuyaku, Satoshi Fuke, Yasuyuki Nasuhara, Toshiaki Morikawa, Satoshi Kondo, and Masaharu Nishimura

Diverse Expression of Antioxidants and Inflammatory Chemokines in Terminal Bronchiolar Epithelium in Chronic Obstructive Pulmonary Disease
Proc Am Thorac Soc 2006 3: 471-472. [Full Text] [PDF]  

Soumyaroop Bhattacharya, Sorachai Srisuma, Dawn L. DeMeo, John J. Reilly, Raphael Bueno, Edwin K. Silverman, and Thomas J. Mariani

Microarray Data–Based Prioritization of Chronic Obstructive Pulmonary Disease Susceptibility Genes
Proc Am Thorac Soc 2006 3: 472. [Full Text] [PDF]  

Section 3.:

William O. C. Cookson

State of the Art. Genetics and Genomics of Chronic Obstructive Pulmonary Disease
Proc Am Thorac Soc 2006 3: 473-475. [Full Text] [PDF]  

Raja T. Abboud, Alison M. Wallace, John C. English, Nestor L. Müller, Harvey Coxson, Peter D. Paré, and Andrew J. Sandford

Relationship of Matrix Metalloproteinase mRNA Expression and Genetic Polymorphisms to Emphysema
Proc Am Thorac Soc 2006 3: 475. [Full Text] [PDF]  

Saadia Eddahibi, Ari Chaouat, Li Tu, Christos Chouaid, Emmanuel Weitzenblum, Bruno Housset, Bernard Maitre, and Serge Adnot

Interleukin-6 Gene Polymorphism Confers Susceptibility to Pulmonary Hypertension in Chronic Obstructive Pulmonary Disease
Proc Am Thorac Soc 2006 3: 475-476. [Full Text] [PDF]  

Craig P. Hersh, Dawn L. DeMeo, Ross Lazarus, Juan C. Celedón, Benjamin A. Raby, John J. Reilly, and Edwin K. Silverman

Genetic Determinants of Functional Impairment in Chronic Obstructive Pulmonary Disease
Proc Am Thorac Soc 2006 3: 476. [Full Text] [PDF]  

Chun Geun Lee, Soojung Cho, Robert J. Homer, and Jack A. Elias

Genetic Control of Transforming Growth Factor-ß₁–induced Emphysema and Fibrosis in the Murine Lung
Proc Am Thorac Soc 2006 3: 476-477. [Full Text] [PDF]  

Becky Mercer, Constance Brinckerhoff, and Jeanine D'Armiento

Activation of the MMP-1 Promoter by Cigarette Smoke in Human Small Airway Epithelial Cells Requires ERK MAP Kinase Signaling: Differential Response of the 1G and 2G Promoter Sequences
Proc Am Thorac Soc 2006 3: 477. [Full Text] [PDF]  

Section 4.:

Alvar Agusti

Thomas A. Neff Lecture. Chronic Obstructive Pulmonary Disease: A Systemic Disease
Proc Am Thorac Soc 2006 3: 478-481. [Full Text] [PDF]  

John R. Hurst, Wayomi R. Perera, Tom M. A. Wilkinson, Gavin C. Donaldson, and Jadwiga A. Wedzicha

Exacerbation Of Chronic Obstructive Pulmonary Disease: Pan-Airway and Systemic Inflammatory Indices
Proc Am Thorac Soc 2006 3: 481-482. [Full Text] [PDF]  

Dwight C. Look, Cecilia L. Chin, Lori J. Manzel, Erin E. Lehman, Alicia L. Humlicek, Lei Shi, Timothy D. Starner, Gerene M. Denning, Timothy F. Murphy, and Sanjay Sethi

Modulation of Airway Inflammation by Haemophilus influenzae Isolates Associated with Chronic Obstructive Pulmonary Disease Exacerbation
Proc Am Thorac Soc 2006 3: 482-483. [Full Text] [PDF]  

Section 5.:

Lawrence Steinman

State of the Art. Four Easy Pieces: Interconnections between Tissue Injury, Intermediary Metabolism, Autoimmunity, and Chronic Degeneration
Proc Am Thorac Soc 2006 3: 484-486. [Abstract] [Full Text] [PDF]  

Andrew K. Sullivan, Philip L. Simonian, Michael T. Falta, Gregory P. Cosgrove, Kevin K. Brown, Brian L. Kotzin, Norbert F. Voelkel, and Andrew P. Fontenot

Activated Oligoclonal CD4⁺ T Cells in the Lungs of Patients with Severe Emphysema
Proc Am Thorac Soc 2006 3: 486. [Full Text] [PDF]  

Laimute Taraseviciene-Stewart, Nana Burns, Donatas Kraskauskas, Mark R. Nicolls, Rubin M. Tuder, and Norbert F. Voelkel

Mechanisms of Autoimmune Emphysema
Proc Am Thorac Soc 2006 3: 486-487. [Full Text] [PDF]  

Aneal Gadgil, Xuehai Zhu, Frank C. Sciurba, and Steven R. Duncan

Altered T-Cell Phenotypes in Chronic Obstructive Pulmonary Disease
Proc Am Thorac Soc 2006 3: 487-488. [Full Text] [PDF]  

Section 6.:

James C. Hogg

State of the Art. Bronchiolitis in Chronic Obstructive Pulmonary Disease
Proc Am Thorac Soc 2006 3: 489-493. [Full Text] [PDF]  

Andrew Churg, Rong D. Wang, and Joanne L. Wright

Cigarette Smoke Causes Small Airway Remodeling by Direct Growth Factor Induction and Release
Proc Am Thorac Soc 2006 3: 493. [Full Text] [PDF]  

Joungjoa Park, Shijing Fang, and Kenneth B. Adler

Regulation of Airway Mucin Secretion by MARCKS Protein Involves the Chaperones Heat Shock Protein 70 and Cysteine String Protein
Proc Am Thorac Soc 2006 3: 493. [Full Text] [PDF]  

Section 7.:

Jack A. Elias, Min Jong Kang, Kristina Crouthers, Robert Homer, and Chun Geun Lee

State of the Art. Mechanistic Heterogeneity in Chronic Obstructive Pulmonary Disease: Insights from Transgenic Mice
Proc Am Thorac Soc 2006 3: 494-498. [Abstract] [Full Text] [PDF]  

Section 8.:

David A. Lomas

Parker B. Francis Lectureship. Antitrypsin Deficiency, the Serpinopathies, and Chronic Obstructive Pulmonary Disease
Proc Am Thorac Soc 2006 3: 499-501. [Abstract] [Full Text] [PDF]  

Dawn DeMeo, Thomas Mariani, Christoph Lange, Stephen Lake, Augusto Litonjua, Juan Celedón, John Reilly, Harold A. Chapman, David Sparrow, Avrum Spira, Jennifer Beane, Victor Pinto-Plata, Frank E. Speizer, Steve Shapiro, Scott T. Weiss, and Edwin K. Silverman

The SERPINE2 Gene Is Associated with Chronic Obstructive Pulmonary Disease
Proc Am Thorac Soc 2006 3: 502. [Full Text] [PDF]  

Section 9.:

Rubin M. Tuder, Toshinori Yoshida, Wadih Arap, Renata Pasqualini, and Irina Petrache

State of the Art. Cellular and Molecular Mechanisms of Alveolar Destruction in Emphysema: An Evolutionary Perspective
Proc Am Thorac Soc 2006 3: 503-510. [Abstract] [Full Text] [PDF]  

Irina Petrache, Viswanathan Natarajan, Lijie Zhen, Terry R. Medler, Amy Richter, Evgeni V. Berdyshev, and Rubin M. Tuder

Ceramide Causes Pulmonary Cell Apoptosis and Emphysema: A Role for Sphingolipid Homeostasis in the Maintenance of Alveolar Cells
Proc Am Thorac Soc 2006 3: 510. [Full Text] [PDF]  

Dawn M. Simon, Meltem C. Arikan, Sorachai Srisuma, Soumyaroop Bhattacharya, Temana Andalcio, Steven D. Shapiro, and Thomas J. Mariani

Epithelial Cell PPAR Is an Endogenous Regulator of Normal Lung Maturation and Maintenance
Proc Am Thorac Soc 2006 3: 510-511. [Full Text] [PDF]  

Section 10.:

Peter M. Henson, Gregory P. Cosgrove, and R. William Vandivier

State of the Art. Apoptosis and Cell Homeostasis in Chronic Obstructive Pulmonary Disease
Proc Am Thorac Soc 2006 3: 512-516. [Full Text] [PDF]  

Konosuke Morimoto, William J. Janssen, Michael B. Fessler, Yi Qun Xiao, Kathleen A. McPhillips, Valeria M. Borges, Jennifer A. Kench, Peter M. Henson, and R. William Vandivier

Statins Enhance Clearance of Apoptotic Cells through Modulation of Rho-GTPases
Proc Am Thorac Soc 2006 3: 516-517. [Full Text] [PDF]  

S. Patrick Nana-Sinkam, Jong Deog Lee, Robert Stearman, Seiichiro Sakao, Sylk Sotto-Santiago, Norbert F. Voelkel, and Mark W. Geraci

Prostacyclin Synthase in Smoking-related Lung Disease
Proc Am Thorac Soc 2006 3: 517. [Full Text] [PDF]  

Min Jong Kang, Chun Geun Lee, Soo Jung Cho, Robert J. Homer, and Jack A. Elias

IFN-–dependent DNA Injury and/or Apoptosis Are Critical in Cigarette Smoke–induced Murine Emphysema
Proc Am Thorac Soc 2006 3: 517-518. [Full Text] [PDF]  

Section 11.:

Eric A. Hoffman, Brett A. Simon, and Geoffrey McLennan

State of the Art. A Structural and Functional Assessment of the Lung via Multidetector-Row Computed Tomography: Phenotyping Chronic Obstructive Pulmonary Disease
Proc Am Thorac Soc 2006 3: 519-532. [Abstract] [Full Text] [PDF]  

Bip Patel, Barry Make, Harvey O. Coxson, Nestor L. Muller, Sreekumar Pillai, Wayne Anderson, Edwin Silverman, David Lomas, and for the GSK COPD International Genetics Network

Airway and Parenchymal Disease in Chronic Obstructive Pulmonary Disease Are Distinct Phenotypes
Proc Am Thorac Soc 2006 3: 533. [Full Text] [PDF]  

Frank C. Sciurba, Fernando J. Martinez, Robert M. Rogers, Barry J. Make, Gerald J. Criner, Ruben M. Cherniack, Sanjay A. Patel, Fanny Chu, Harvey O. Coxson, Amir Sharafkhaneh, Mark Elliot, James D. Luketich, and James C. Hogg

Relationship between Pathologic Characteristics of Peripheral Airways and Outcome after Lung Volume Reduction Surgery in Severe Chronic Obstructive Pulmonary Disease
Proc Am Thorac Soc 2006 3: 533-534. [Full Text] [PDF]  

Section 12.:

Jerome S. Brody and Avrum Spira

State of the Art. Chronic Obstructive Pulmonary Disease, Inflammation, and Lung Cancer
Proc Am Thorac Soc 2006 3: 535-537. [Abstract] [Full Text] [PDF]  

Maria R. Bonsignore, Paolo Palange, Ugo Testa, Alice Huertas, Rosa Antonucci, Pietro Serra, and Giovanni Bonsignore

Circulating CD34+ Cells Are Decreased in Chronic Obstructive Pulmonary Disease
Proc Am Thorac Soc 2006 3: 537-538. [Full Text] [PDF]  

Conference Summary:

William MacNee

Conference Summary
Proc Am Thorac Soc 2006 3: 539-542. [Full Text] [PDF]  

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