SYMPOSIUM: THOMAS L. PETTY ASPEN LUNG CONFERENCE: LUNG INJURY AND REPAIR

David W. H. Riches, Gregory P. Cosgrove, and Stephen K. Frankel

Introduction and Perspective
Proc Am Thorac Soc 2008 5: 287-289 [Full Text] [PDF]  

Thomas L. Petty

Initial Observations That Led to the Definition of ARDS
Proc Am Thorac Soc 2008 5: 290 [Full Text] [PDF]  

State of the Art

Get checked abstract Thomas R. Martin

Interactions between Mechanical and Biological Processes in Acute Lung Injury
Proc Am Thorac Soc 2008 5: 291-296 [Abstract] [Full Text] [PDF]  

Get checked abstract Michael A. Matthay

Treatment of Acute Lung Injury: Clinical and Experimental Studies
Proc Am Thorac Soc 2008 5: 297-299 [Abstract] [Full Text] [PDF]  

Get checked abstract Robert M. Strieter

What Differentiates Normal Lung Repair and Fibrosis?: Inflammation, Resolution of Repair, and Fibrosis
Proc Am Thorac Soc 2008 5: 305-310 [Abstract] [Full Text] [PDF]  

Get checked abstract Derek C. Radisky and Jennifer A. Przybylo

Matrix Metalloproteinase–induced Fibrosis and Malignancy in Breast and Lung
Proc Am Thorac Soc 2008 5: 316-322 [Abstract] [Full Text] [PDF]  

Get checked abstract Diane S. Krause

Bone Marrow–derived Cells and Stem Cells in Lung Repair
Proc Am Thorac Soc 2008 5: 323-327 [Abstract] [Full Text] [PDF]  

Get checked abstract Barry R. Stripp and Susan D. Reynolds

Maintenance and Repair of the Bronchiolar Epithelium
Proc Am Thorac Soc 2008 5: 328-333 [Abstract] [Full Text] [PDF]  

Get checked abstract Sem H. Phan

Biology of Fibroblasts and Myofibroblasts
Proc Am Thorac Soc 2008 5: 334-337 [Abstract] [Full Text] [PDF]  

Get checked abstract Ryan Kamp, Xiaoguang Sun, and Joe G. N. Garcia

Making Genomics Functional: Deciphering the Genetics of Acute Lung Injury
Proc Am Thorac Soc 2008 5: 348-353 [Abstract] [Full Text] [PDF]  

Parker B. Francis Lectureship

Get checked abstract Yun Lu, Tadashi Okubo, Emma Rawlins, and Brigid L. M. Hogan

Epithelial Progenitor Cells of the Embryonic Lung and the Role of MicroRNAs in Their Proliferation
Proc Am Thorac Soc 2008 5: 300-304 [Abstract] [Full Text] [PDF]  

Thomas A. Neff Lecture

Get checked abstract Geoffrey J. Laurent, Robin J. McAnulty, Michael Hill, and Rachel Chambers

Escape from the Matrix: Multiple Mechanisms for Fibroblast Activation in Pulmonary Fibrosis
Proc Am Thorac Soc 2008 5: 311-315 [Abstract] [Full Text] [PDF]  

Roger S. Mitchell Lecture

Get checked abstract Tatiana Kisseleva and David A. Brenner

Fibrogenesis of Parenchymal Organs
Proc Am Thorac Soc 2008 5: 338-342 [Abstract] [Full Text] [PDF]  

Giles F. Filley Lecture

Get checked abstract David A. Schwartz

Genetic Analysis of Sporadic and Familial Interstitial Pneumonia
Proc Am Thorac Soc 2008 5: 343-347 [Abstract] [Full Text] [PDF]  

Conference Summary

Norbert F. Voelkel

Conference Summary
Proc Am Thorac Soc 2008 5: 354-357 [Full Text] [PDF]  

Abstracts

George Su, Nanyan Wu, Amha Atakilit, Jiyeun Kate Kim, and Dean Sheppard

Integrins vβ3 and vβ5 Reciprocally Regulate Pulmonary Endothelial Barrier Function through Differential Effects on the Actin Cytoskeleton
Proc Am Thorac Soc 2008 5: 358 [Full Text] [PDF]  

Lorraine B. Ware, Julie A. Bastarache, Ling Wang, and Michael A. Matthay

Modulation of Intra-alveolar Fibrin Deposition by the Alveolar Epithelium In Acute Lung Injury: Clinical and Experimental Evidence
Proc Am Thorac Soc 2008 5: 358-359 [Full Text] [PDF]  

Michael C. Winter, Sandra S. Shasby, and D. Michael Shasby

PAR2 Interrupts E-Cadherin Adhesion and Decreases the Transepithelial Resistance of Epithelia by Phosphorylating Tyrosines 489 and 654 of Beta-Catenin
Proc Am Thorac Soc 2008 5: 359 [Full Text] [PDF]  

Sina A. Gharib, W. Conrad Liles, and William A. Altemeier

Dissecting the Lung's Transcriptional Program during Noninjurious Mechanical Ventilation
Proc Am Thorac Soc 2008 5: 359 [Full Text] [PDF]  

Emma L. Rawlins and Brigid L. M. Hogan

Epithelial Progenitor Cells in Lung Development and Repair
Proc Am Thorac Soc 2008 5: 360 [Full Text] [PDF]  

Johannes C. Schittny, Sonja I. Mund, and Marco Stampanoni

Evidence and Structural Mechanism for Late Lung Alveolarization
Proc Am Thorac Soc 2008 5: 360 [Full Text] [PDF]  

Anita I. Sen, Robert F. Foronjy, Takayuki Shiomi, and Jeanine M. D'Armiento

Loss of MMP-13 Delays Inflammatory Response after Acute Hyperoxic Lung Injury
Proc Am Thorac Soc 2008 5: 360-361 [Full Text] [PDF]  

Bin Shan, Tso-Pang Yao, Ying Zhuo, Hong T. Nguyen, Ross C. Klingsberg, and Joseph A. Lasky

Histone Deacetylase 6 Regulates TGF-β1–mediated Epithelial–Mesenchymal Transition
Proc Am Thorac Soc 2008 5: 361 [Full Text] [PDF]  

Gustavo Matute-Bello, Mark M. Wurfel, Janet S. Lee, Charles W. Frevert, Steven Shapiro, and Thomas R. Martin

MMP-12 Mediates Fibrosis after Lung Injury in Mice
Proc Am Thorac Soc 2008 5: 361-362 [Full Text] [PDF]  

Viranuj Sueblinvong, Meagan A. Goodwin, Philip L. Eisenhauer, Ira M. Bernstein, Jeffrey L. Spees, and Daniel J. Weiss

Cord Blood–derived Mesenchymal Stem Cells Can Participate in Lung Epithelial Remodeling In Vivo
Proc Am Thorac Soc 2008 5: 362 [Full Text] [PDF]  

Hiroshi Kubo, Ahmed E. Hegab, Mei He, Kota Ishizawa, and Mitsuhiro Yamada

Endogenous Lung Stem Cells Increased after Lung Injury
Proc Am Thorac Soc 2008 5: 362-363 [Full Text] [PDF]  

Andrew M. Tager, Peter LaCamera, Barry S. Shea, Gabriele S. Campanella, Moisés Selman, Zhenwen Zhao, Vasiliy Polosukhin, John Wain, Banu A. Karimi-Shah, Nancy D. Kim, William K. Hart, Eli C. Poorvu, Sarah F. Brooks, Scott D. Bercury, Annie Pardo, Timothy S. Blackwell, Yan Xu, Jerold Chun, and Andrew D. Luster

The Lysophosphatidic Acid Receptor LPA₁ Links Pulmonary Fibrosis to Lung Injury by Mediating Fibroblast Recruitment and Vascular Leak
Proc Am Thorac Soc 2008 5: 363 [Full Text] [PDF]  

Yan Y. Sanders, José Cisneros, Gerard Nuovo, Moises Selman, and James S. Hagood

Epigenetic Regulation Mediates Thy-1 Gene Silencing and Induction of the Myofibroblast Phenotype
Proc Am Thorac Soc 2008 5: 363-364 [Full Text] [PDF]  

Qiang Ding, Candece L. Gladson, Hongjui Wu, and Mitchell A. Olman

Myofibroblast Differentiation Is Negatively Regulated by FAK-related Non-kinase
Proc Am Thorac Soc 2008 5: 364 [Full Text] [PDF]  

Justin D. Mih and Daniel J. Tschumperlin

Lung Fibroblast Behavior Is Tuned by Substrate Stiffness
Proc Am Thorac Soc 2008 5: 364-365 [Full Text] [PDF]  

Peggy O'Cain, Pallavi P. Patwari, Melita E. Smith, Mary K. Dahmer, and Michael W. Quasney

The Surfactant Protein B +1580 Polymorphism and Lung Injury in Children with Community-acquired Pneumonia
Proc Am Thorac Soc 2008 5: 365 [Full Text] [PDF]  

Dorota L. Stankowska, Rafal Fudala, and Anna K. Kurdowska

Mechanism of Epithelial Injury Triggered by Anti–IL-8 Autoantibody:IL-8 Immune Complexes
Proc Am Thorac Soc 2008 5: 365-366 [Full Text] [PDF]  

Jennifer H. Madenspacher, Kathleen A. Smoak, Samithamby Jeyaseelan, Belinda Williams, Katie R. Poch, Jerry A. Nick, G. Scott Worthen, and Michael B. Fessler

Liver X Receptor Agonists Modify Pulmonary Innate Immunity
Proc Am Thorac Soc 2008 5: 366 [Full Text] [PDF]  

Kimberly E. White, Qiang Ding, Lorraine B. Ware, Bethany B. Moore, Marc Peters-Golden, Michael A. Matthay, and Mitchell A. Olman

IL-1β Mediates Fibroblast Proliferation in Acute Lung Injury through Differential Utilization of Prostanoid Receptors by Prostaglandin E2
Proc Am Thorac Soc 2008 5: 366-367 [Full Text] [PDF]  

Narsa M. Reddy, Steven R. Kleeberger, Masayuki Yamamoto, and Sekhar P. Reddy

Nrf2-dependent Glutathione-regulated Transcriptional Program Controls Lung Type II Cell Proliferation and Protection against Oxidative Stress
Proc Am Thorac Soc 2008 5: 367 [Full Text] [PDF]  

Mari Nakamura, Hong Wei Chu, Edward D. Chan, and Dennis R. Voelker

Surfactant Phospholipids Suppress the Inflammation of Bronchial Epithelium Induced by TLR2 and TLR3 Ligands
Proc Am Thorac Soc 2008 5: 367-368 [Full Text] [PDF]  

Anita J. Reddy and Steven R. Kleeberger

Knockdown of NQO1 Leads to Decreased Production of ROS after Exposure to Hyperoxia
Proc Am Thorac Soc 2008 5: 368 [Full Text] [PDF]  

Michael Koval, Xian Fan, Alberto L. Fernandez, Latoya N. Johnson, Pratibha C. Joshi, and David M. Guidot

Effects of Alcohol and GM-CSF on Alveolar Tight Junctions
Proc Am Thorac Soc 2008 5: 368-369 [Full Text] [PDF]  

Rajesh Bhagat, Elise P. Gomez-Sanchez, Mary P. Warden, Angela de Rodriguez, John Spurzem, Terry M. Dwyer, and Celso E. Gomez-Sanchez

Role of Mineralocorticoid Receptor in Paraquat-induced Rat Lung Fibrosis
Proc Am Thorac Soc 2008 5: 369 [Full Text] [PDF]  

Eva Nozik-Grayck, Kevin P. Roush, Joseph Albietz, Amelia Hopkins, Hagir B. Suliman, and Kurt R. Stenmark

Extracellular Superoxide Induces Egr-1 and Promotes Hypoxic Pulmonary Vascular Remodeling
Proc Am Thorac Soc 2008 5: 369 [Full Text] [PDF]  

Timothy M. Moore

Pulmonary Microvascular Endothelial Cells Expressing CD40 Exhibit Increased Permeability to sCD40L
Proc Am Thorac Soc 2008 5: 370 [Full Text] [PDF]  

Dereje S. Ayo, Allen S. Ensminger, Gang Liu, and Nicholas E. Vlahakis

Deformation-induced Lung Cell Injury Is Glucose Concentration and Cell Type Dependent
Proc Am Thorac Soc 2008 5: 370 [Full Text] [PDF]  

Roelie M. Wösten-van Asperen, Rene Lutter, Jack J. Haitsma, Maruschka P. Merkus, Job B. van Woensel, Sandrine Florquin, Burkhard Lachmann, and Albert P. Bos

Pulmonary Angiotensin-converting Enzyme Mediates Ventilator-induced Lung Injury in Rats
Proc Am Thorac Soc 2008 5: 371 [Full Text] [PDF]  

Ashok N. Babu, Tomohiro Murakawa, Norbert F. Voelkel, Martin R. Zamora, Peter M. Henson, and Mark R. Nicolls

Functional Microcirculation Is Lost in Early Airway Fibrosis
Proc Am Thorac Soc 2008 5: 371 [Full Text] [PDF]  

Julie A. Bastarache, Ling Wang, Nancy E. Wickersham, Kurt H. Albertine, Michael A. Matthay, and Lorraine B. Ware

Intra-Alveolar Tissue Factor Pathway Inhibitor Is Not Sufficient to Block Tissue Factor Procoagulant Activity
Proc Am Thorac Soc 2008 5: 372 [Full Text] [PDF]  

Kummarapurugu B. C. Apparao, Donna R. Newman, Huiying Zhang, Jody Khosla, and Philip L. Sannes

Sulfated Extracellular Matrix Modulates Differentiation of Human Alveolar Type II Cells In Vitro
Proc Am Thorac Soc 2008 5: 372 [Full Text] [PDF]  

Theodore J. Kottom and Andrew H. Limper

A Rapid Screening Method for Compounds Displaying Synergy for the Treatment of Lung Fibrosis
Proc Am Thorac Soc 2008 5: 373 [Full Text] [PDF]  

Hara Levy, Amy Murphy, Fei Zou, Craig Gerard, Barbara J. Klanderman, Brooke Schuemann, Ross Lazarus, K. Christopher García, Juan C. Celedón, Mitch Drumm, Mary K. Dahmer, Michael W. Quasney, Michael R. Knowles, Gerald B. Pier, Christoph Lange, and Scott T. Weiss

Polymorphisms in the IL-1 Gene Family and Lung Disease Severity in Patients with Cystic Fibrosis
Proc Am Thorac Soc 2008 5: 373-374 [Full Text] [PDF]  

Kechun Tang, Jaret L. Malloy, and Ellen C. Breen

Vascular Endothelial Growth Factor Is Essential for Maintaining Pulmonary Surfactant Protein D Expression In Vivo
Proc Am Thorac Soc 2008 5: 374 [Full Text] [PDF]  

Mary K. Dahmer, Pallavi P. Patwari, Peggy A. O'Cain, Denise M. Goodman, Julia Krushkal, Grant W. Somes, Caiqin Liu, Melita E. Smith, and Michael W. Quasney

Interleukin-1 Receptor Antagonist Intron 2 Polymorphism and Lung Injury in Children with Community-acquired Pneumonia
Proc Am Thorac Soc 2008 5: 374-375 [Full Text] [PDF]  

Patricia L. Jackson, J. Edwin Blalock, and Amit Gaggar

Neutrophil Chemotactic Collagen Fragments Are Generated from Cystic Fibrosis Sputum
Proc Am Thorac Soc 2008 5: 375 [Full Text] [PDF]  

Cheryl L. Fattman, German Torres, Brian L. Brockway, Barry R. Stripp, and Luis A. Ortiz

Remodeling of the Respiratory Unit in Silica-exposed Mice
Proc Am Thorac Soc 2008 5: 375 [Full Text] [PDF]  

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